Drug Standards
Medchemexpress LLC Dactolisib (Tosylate) | 1028385-32-1 | C37H31N5O4S | 1 ML
Dactolisib Tosylate is a dual PI3K and mTOR kinase inhibitor. It effectively blocks the dysfunctional activation of the PI3K pathway, inducing G1 arrest in human tumor cell lines. This compound is well tolerated in vivo, induces disease stasis when administered orally, and enhances the efficacy of other anticancer agents.
- Dual PI3K and mTOR kinase inhibitor
- Inhibits both mTORC1 and mTORC2
- Induces G1 arrest in human tumor cell lines
- Active against mutant PI3Kα
- Reduces cell proliferation in PTEN-null cell lines
- Well tolerated in vivo
- Enhances efficacy of other anticancer agents
Sigma Aldrich Fine Chemicals Biosciences Cysteine hydrochloride monohydrate European Pharmacopoeia (EP) Reference Standard | 7048-04-6 | MFCD00065606 |
Cysteine hydrochloride monohydrate European Pharmacopoeia (EP) Reference Standard | Mol Wt: 175.63 | 7048-04-6 | MFCD00065606 |
Medchemexpress LLC Dactolisib (tosylate) | 1028385-32-1 | C37H31N5O4S | 200 MG
Dactolisib Tosylate (BEZ235 Tosylate) is a dual PI3K and mTOR kinase inhibitor. It inhibits mTORC1 and mTORC2, and is active against mutant PI3KαE545K or PI3KαH1047R. This compound effectively and specifically blocks dysfunctional activation of the PI3K pathway, inducing G1 arrest in human tumor cell lines. It is well tolerated and enhances the efficacy of other anticancer agents.
Sigma Aldrich Fine Chemicals Biosciences Methotrexate Related Compound C United States Pharmacopeia (USP) Reference Standard | 2410-93-7 | 50MG
Methotrexate Related Compound C United States Pharmacopeia (USP) Reference Standard | Mol Wt: 455.42 | 2410-93-7 | 50MG
Medchemexpress LLC Ticagrelor impurity 26 | 1644461-85-7 | 99.4% | C23H28F2N6O5S | 5 MG
Ticagrelor impurity 26 is an off-white to light yellow solid with a purity of 99.4%. This chemical is for research use only and intended for experienced personnel in appropriately equipped and authorized facilities. It is stable under recommended storage conditions, but incompatible with strong acids/alkalis, and strong oxidizing/reducing agents. Hazardous decomposition products may be emitted under fire conditions.
- Off-white to light yellow solid appearance
- Purity (LCMS) of 99.4%
- Stable under recommended storage conditions
- For research use only
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Ticagrelor impurity 16 | 2096989-56-7 | 99.5% | C23H28F2N6O4S | 5 MG
Ticagrelor impurity 16 is an impurity of Ticagrelor, intended for research use only. It is a solid with a molecular weight of 522.57.
- Impurity of ticagrelor
- Solid form
- Molecular weight of 522.57
- Intended for research use only
- Store at room temperature for 3 years
- Store in solvent at -80°C for 2 years
- Store in solvent at -20°C for 1 year
Medchemexpress LLC Chitosan oligosaccharide (COS) | 148411-57-8 | 91.0% | 5 G
Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine. It activates AMPK and inhibits inflammatory signaling pathways including NF-κB and MAPK pathways.
- Activates AMPK.
- Inhibits inflammatory signaling pathways including NF-κB and MAPK pathways.
- Possesses anti-inflammation, anti-cancer, and anti-diabetes effects.
- Interrupts cancer progression by modulating signaling proteins/pathways.
- Induces death in various cancer cell types.
- Suppresses production of proinflammatory cytokines.
- Demonstrates anti-inflammatory effect on lymphocyte activation.
- Inhibits UV-induced macroscopic appearance in mice skin, reducing signs of photoaging.
Selleck Chemical LLC Ganciclovir 50mg 82410-32-0 RS-21592, BW-759
Ganciclovir (RS-21592, BW-759) is an antiviral drug for feline herpesvirus type-1 with IC50 of 5.2 ?M in a cell-free assay. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Betahistine
Betahistine is an antivertigo drug that primarily acts as a histamine H1 agonist
Medchemexpress LLC Doxycycline hyclate (Standard) | 24390-14-5 | 512.94 | 50 MG
Doxycycline hyclate (Standard) is the analytical standard of Doxycycline hyclate. It is an antibiotic, an orally active and broad-spectrum metalloproteinase (MMP) inhibitor, showing antibacterial activity and anti-cancer cell proliferation activity. It is intended for research and analytical applications.
- Used as an analytical standard.
- Reference standard supplied assay.
- Used in qualitative, quantitative, and methodological research experiments.
- Applicable in HPLC, GC, and MS.
- Shows antibacterial activity.
- Shows anti-cancer cell proliferation activity.
- Orally active and broad-spectrum metalloproteinase (MMP) inhibitor.
Medchemexpress LLC (±)-Nornicotine | 5746-86-1 | 148.20 | 10 MM * 1 ML
(±)-Nornicotine is a major metabolite of Nicotine. It is a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. It can be used in the research of atherosclerosis, Alzheimer's disease, and schizophrenia.
- Promotes cell migration, disrupts adherens junctions and tight junctions
- Induces F-actin depolymerization
- Maintains self-administration behavior in rats
Sigma Aldrich Fine Chemicals Biosciences Anastrozole United States Pharmacopeia (USP) Reference Standard | 120511-73-1 | 200MG
Anastrozole United States Pharmacopeia (USP) Reference Standard | Mol Wt: 293.37 | 120511-73-1 | 200MG